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Nephthys Build Guide

Nephthys portrait

Nephthys

Destroyer class icon
Kemich
SSR Fire Destroyer DPS

Nephthys is a SSS fire AOE destroyer who punishes shields: her passive deals +36.7% damage to shielded enemies (and +75.6% more at 5 [Hellfire Sin] stacks), her auto nukes ALL enemies for 488.9% while stacking [Hellfire Sin], and her ULT channels 12 meteor hits that each shred DEF. She deletes shielded packs and bosses while stacking her own damage amplifier.

Skill Priority

Skill level recommendations:

1
Auto Skill: Blazing Explosion
Level 14
Cooldown: 5.0s Deals 488.9% attack power as fire damage to all enemies and inflicts the [Hellfire Sin] debuff, reducing healing received by 5.5% and critical hit resistance by 5.5%, up to 5 stacks, lasting 10 seconds. Simultaneously grants self the [Fiery Avatar] debuff, increasing balze damage and ultimate skill damage by 4%, up to 5 stacks.
2
Ultimate: Blazing Rain
Level 14
Energy Cost: 3 Cooldown: 3.0s Summons a shower of meteors, dealing 90.6% attack power as fire damage to all enemies every 0.5 seconds. The channel lasts 6 seconds (can be interrupted during channeling). Each attack inflicts [Molten Armor], reducing the target's defense by 1.25%, stacking up to 20 times. If Nephthys successfully completes the entire cast without interruption, she will deal an additional 271.7% attack power as balze damage to all enemies at the end.
3
Passive: No self, no heaven
Level 14
All damage dealt to enemy units with a Shield is increased by 36.7%. When dealing damage: If the opponent has 5 stacks of [Infernal Sin], the damage you deal to them is increased by 75.6%. If you have 5 stacks of [Blazing Incarnation], you take less damage 48.9% and gain a shield equal to your attack power 24.4% when you take damage. The shield has a 4-second cooldown.
4
Normal Attack: Pillar of Blazing Flame
Level 14
Cooldown: 2.0s Deals 93.3% attack damage as fire damage to all enemy units.

Recommended Memory Cards

These are the best memory cards for Nephthys:

A Dream of Peace memory card
A Dream of Peace ★ Exclusive
Must Have
Attack power increased by 60%, and ultimate skill damage increased by 50%. Ultimate skill penetration against enemy defense increases by 24%. If the enemy has a shield, ultimate skill damage against them is increased by 50%.
Note: Exclusive card: +60% ATK, +50% ULT damage and +24% ULT defense penetration. Every line multiplies her meteor channel.
Stats: HP 5,040 / ATK 780 / DEF 474

Alternative Memory Cards

Good alternative options if you don't have the recommended cards:

Night of Blood and Storm memory card
Night of Blood and Storm
Attack increases by 40%, after a team Supporter uses an ULT, the wearer's ULT damage increases by 40% for 5 seconds
Stats: HP 5,040 / ATK 780 / DEF 474
The Servant's Aspiration memory card
The Servant's Aspiration
Critical Damage increases by 72%. For each enemy unit present on the field, normal attack damage increases by 12%, up to a maximum of 4 times.
Stats: HP 5,040 / ATK 780 / DEF 474
Unreserved love memory card
Unreserved love
Attack power increased by 40%; damage over time increased by 40%. When dealing damage over time, the enemy takes 24% more damage for 3 seconds. Damage dealt to enemies with shields is increased by 35%.
Stats: HP 5,040 / ATK 780 / DEF 474

Runes Priorities

Focus on these rune stats for Nephthys:

Primary Stat:
Attack%
Secondary Stat:
Crit Rate

Highly Recommended Stats:

ATK% Crit Rate%

Additional Stats:

Crit DMG% Penetration ATK
Build Note: Multipliers are large, so % damage and crit scale harder than flat ATK: element damage on position 5, crit on position 4.

Recommended Rune Sets:

Hepha.webp rune (4-piece)
4-piece
+
Beth rune (2-piece)
2-piece
Hepha 4-piece + Beth 2-piece
2-piece (Hepha): Blaze damage increased by 10%
4-piece (Hepha): When dealing Blaze attribute Ultimate Skill damage, Critical Rate is increased by 12% and Attack Power is increased by 16%
2-piece (Beth): Critical Rate increases by 6%

Alternative Builds:

Beth rune (4-piece)
4-piece
+
Hepha.webp rune (2-piece)
2-piece
Beth 4-piece + Hepha 2-piece
2-piece (Beth): Critical Rate increases by 6%
4-piece (Beth): When HP is above 80%, Critical Damage increases by 24%
2-piece (Hepha): Blaze damage increased by 10%

Main Stats by Position

Recommended main stats for each rune position for Nephthys:

Position 1: Fixed Main Stat

HP (Flat Value)

Always HP - no other options

Position 2: Fixed Main Stat

Attack (Flat Value)

Always Attack - no other options

Position 3: Fixed Main Stat

Defense (Flat Value)

Always Defense - no other options

Position 4: Variable Main Stats

Available Options:
Healing Effectiveness (%) Critical Rate (%) Critical Damage (%) Attack Penetration (%) Attack (%) HP (%) Defense (%)

Pick the recommended stat pair that matches the rune build below.

Position 5: Variable Main Stats

Available Options:
Wind Attribute Damage (%) Fire Attribute Damage (%) Ice Attribute Damage (%) Holy Attribute Damage (%) Chaos Attribute Damage (%) Attack (%) HP (%) Defense (%)

Position 6: Variable Main Stats

Available Options:
Attack (%) HP (%) Defense (%)

Awakening Priority

A2 is the biggest early jump, then A4. A3/A5 raise skill level caps (+2 each) and are dupe-gated: take A6 last for the team-wide bonus.

A1 Good

Attack power increased by 25%, and the first ultimate skill used after entering the arena does not consume energy. After using the skill, gain 1 stack of [Flame Power], which increases ultimate skill damage by 12.5%, up to a maximum of 5 stacks.

A2 Very Good

Upon entering the arena, you immediately gain 3 stacks of [Blazing Avatar], increasing critical hit damage by 30%. When [Blazing Avatar] reaches 5 stacks, ultimate skill damage is increased by 50%.

A3 Mid

[Normal Attack], [Skill], [ULT] and [Passive] level and level cap +2

A4 Good

Attack power increased by 30%, critical hit damage increased by 30%. For the first 5 seconds upon entering the battlefield, all enemies' critical hit resistance is reduced by 30%.

A5 Mid

[Normal Attack], [Skill], [ULT] and [Passive] level and level cap +2

A6 Good

Ultimate skill damage ignores 25% of the target's elemental resistance.

Team Synergy

Good Teammates:

BorsVeronicaMedusaOdinMorgan Le FayThor

Bors's ATK window on top of her 5-stack passive is her peak damage combo.